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To further confirm that the p62-Keap1-NRF2 axis is responsible for the high expression of GPX4 in EBV-infected cells, we examined the effect of NRF2 on GPX4 expression in EBV-negative and EBV-positive NPC cells using siRNAs against NRF2

Moreover, activated Nrf2 can also dock on the AREs in Mfn2 gene promoter to promote mitochondrial fusion (Hu et al., 2021)

This compound serves as a frontline defense against free radicalsunstable molecules that can damage cells if left unchecked

Its like a slow-release energy bar for your cells

doi:10.1155/2016/3204083 Le Donne M, Metro D, Alibrandi A, Papa M, Benvenga S

10.1016/j.ejphar.2016.07.026 160 SasakiH.HamataniT.KamijoS.IwaiM.KobanawaM.OgawaS.et al (2019)