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Patients on the top oral maintenance dose lost a mean 14 to 16 percent of body weight over 64 weeks compared with a small change on placebo

But issues can arise e.g., impurities, immunogenicity to cause concern

Cardiovascular examination revealed the absence of pallor, blood pressure of 130/86 mm Hg, heart rate of 72 beats/min with a regular rhythm, and no signs of heart failure

Nunez NA, Joseph B, Pahwa M, et al

While not FDA-approved specifically for liver disease, growing data support their off-label use in MASLD under physician guidance

With minimal to no downtime, patients may experience mild redness that usually subsides within minutes, allowing them to return to regular activities immediately