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doi: 10.1111/j.1469-1809.2007.00398.x 6 Martnez-CortsGSalazar-FloresJGabriela Fernndez-RodrguezLRubi-CastellanosRRodrguez-LoyaCVelarde-FlixJSet al

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So if you look at exercise, you're up regulating cortisol, obviously chronically is very inflammatory, acutely is necessary for this hormetic effect of we get stronger, right, you stress the bone, obviously we rebuild, regenerate with osteoblast, same thing with the muscle, that's how we develop strength