Cardiovascular Consequences of Repetitive Arousals over the Entire Sleep Duration
The early human evidence is suggestive
Melatonin mitigates oxidative stress, inflammation processes, and cell apoptosis by upregulating the Nrf2 signaling pathway and downregulating COX-2 protein levels (135), as well as SOD, GPx, CAT, and Bcl-2 activities (136)
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