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As highlighted elsewhere [184], neurons rely heavily on astrocytes for redox balance, creating a compartmentalized and interdependent defense system

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Symptoms of POTS may include: Dizziness or lightheadedness Increased heart rate upon standing Heart palpitations or chest pain Extreme fatigue, especially in the morning Sleep disturbances Headaches Brain fog Exercise intolerance Shakiness or anxiety Visual disturbances Intolerances to heat or exercise Intolerance to prolonged standing POTS has been linked to other underlying health conditions and imbalances, including other autoimmune conditions, Ehlers-Danlos syndrome (EDS), mast cell activation syndrome (MCAS), chronic fatigue syndrome, adrenal dysfunction, and irritable bowel syndrome (IBS)

The majority of SAPHs are based on L-amino acids, which are naturally found and processed by the human body, making them low in terms of immunogenicity and inflammatory properties [181,182]

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