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doi: 10.1093/jxb/erj175

Reported Sex-Based Variability in the Literature Where sex-based data does appear, researchers generally attribute observed variability to differences in baseline endogenous IGF-1 and growth hormone signaling between male and female physiology, rather than to any fundamental difference in how IGF-1 LR3 binds or activates the IGF-1 receptor

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[DOI] [PubMed] [Google Scholar] 69.McClain CJ, Twyman DL, Ott LG, Rapp RP, Tibbs PA, Norton JA, et al

lower or similar proportions of both men and women experienced events with semaglutide vs placebo, and p-values for interaction were nonsignificant (p = 0.46, p = 0.34 and p = 0.74, respectively, for each endpoint) (Fig

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