GLP-1 is a multifaceted hormone, and the use of its analogs is associated with broad metabolic effects: they increase insulin secretion, decrease glucagon release, increase glucose uptake in muscles, decrease glucose production in the liver, improve lipid profile, slow gastric emptying, and increase satiety leading to weight loss (40)
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[19,20] Use it despite higher copays Request a tier exception for lower costs Apply Lilly Savings Card to reduce costs to $25/month (commercial insurance only) Go to Step 3: Start the Prior Authorization Process Scenario: Step Therapy Required Your insurance requires you to try other medications (like metformin) first before approving Mounjaro
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Overviews of some of the major studies are presented here
The maximal therapeutic dose recommended by the FDA is 4 g/day
