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These gaps underscore the need for future research to move beyond descriptive associations, toward mechanistic dissection of pathway integration, cell type-specific functions, and clinical validation of biomarkers and targeted therapies

During the acute phase of the virus, the immune system launches a massive inflammatory response, generating enormous amounts of reactive oxygen species (ROS) to destroy the invading pathogen

The topical use of furazolidone and nitrofurazone was prohibited in 2002

Ultraviolet radiation is one of the strongest triggers of melanin production

Jastreboff PJ

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