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Common side effects include nausea (most common), vomiting, diarrhea, constipation, abdominal pain, and fatigue
Along with other B vitamins (folate, vitamin B 12 , and vitamin B 6 ), higher dietary riboflavin intakes have been associated with lower plasma concentrations of homocysteine (12)
This is no coincidence, as glutathione plays an absolutely critical role in liver function, acting as the first line of defence against oxidative stress, supporting detoxification pathways, and helping to neutralise harmful compounds before they can damage liver cells
However, natural glutathione synthesis in these cells relies on the recycling of its constituents, and as a consequence, the increase in glutathione circulating in the blood can still support this process