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Higdon J, Drake V, Angelo G, Delage B, Carr A, Michels A

Growth hormone releasing peptide-2 (GHRP-2), like ghrelin, increases food intake in healthy men

It also actively delivers anti-inflammatory and pro-motility benefits

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Therefore, Gene Ontology (GO) and the Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were carried out on the DEGs to explore the potential functions of the top 10 mostly changed terms (Fig

This pattern mirrors other real-world reports showing that discontinuation of semaglutide often leads to partial or full weight regain, emphasizing the chronic nature of obesity and the pharmacologic principle that treatment efficacy is contingent upon sustained use [24]