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Costa-Moreira et al., Exosomal glypican-1 discriminates pancreatic ductal adenocarcinoma from chronic pancreatitis

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53 Therapeutic targeting of cardiac proteostasis The recognition that proteostasis failure contributes directly to cardiovascular disease has accelerated the development of therapeutic strategies aimed at restoring protein quality control rather than targeting isolated downstream manifestations

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38,39,40,41 Simultaneously, this metabolic alteration benefits T eff cells by reducing their reliance on oxygen for energy production, which enables them to maintain cytokine production and cytolytic activity even when they migrate into microenvironments within solid tumors that have low oxygen levels

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The views and nutritional advice expressed by Pacifica are not intended to be a substitute for conventional medical service

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126 In the CNS, dystrophin is mainly expressed in protoplasmic astrocytes in neocortex and in velate astrocytes and Bergmann glia in the cerebellum

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