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Last but not least, given the recency of these prescribing trends, no long-term data on the next-generation effects of these medications is available, leading to several uncertainties about the possibility and implications of long-term use

Once PUFA-containing phospholipids become integrated into cell membranes, they are highly susceptible to peroxidation

Also, these are mostly used with internal supplementation for better overall results

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Meanwhile, employers are still grappling with unknowns associated with GLP-1 drugs, namely side effects and still-emerging long-term clinical studies, and the effectiveness of cost control tools like prior authorization and step therapy. But as evidence of the benefits of using the drugs for weight loss continues to grow, along with increased employee demand, it looks like many employers might add coverage

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