6 days after injection, 25 mice were randomly divided into five groups ( n = 5)
Membrane-incorporated PUFAs serve as primary targets for ROS-mediated oxidation, with their oxidative susceptibility increasing proportionally to the number of conjugated double bonds (Rouzer and Marnett, 2003), following the initiation of oxidation, free radicals exhibit dual propagation mechanisms: intramolecular migration within lipid bilayers or intermolecular chain reactions amplifying oxidative damage (Samovich et al., 2024)
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One of the most studied ingredients in this general category is berberine - a plant alkaloid found in goldenseal, barberry, and Oregon grape