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Patients with type 2 diabetes treated with metformin and the GLP-1R agonist exenatide for 1 year display significantly reduced circulating TG, apoB48, and FFA following an early meal (50 g of fat, 75 g of carbohydrates, 35 g of protein)

Nat Rev Nephrol

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If bile is too concentrated with cholesterol or if there arent enough bile salts, stones can develop

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Prepackaged meals add up over time, not everyone enjoys eating mostly packaged food, and because the plan does not include a lasting maintenance structure, weight regain is common once you return to normal eating