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Drug design challenges Several issues must be addressed concerning the development of an efficacious drug to treat AD: (1) the drug must penetrate the BBB to influence damaged neurons in memory-associated brain structures

PMID: 252 WangTWangSLiZXieJDuKHouJ

Chromatographic separation was achieved on a 75 m inner diameter, 75 cm long EasySpray column (Thermo Fisher Scientific) using a 90-min gradient elution

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10.1056/NEJMoa2301972 36 JastreboffA