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Proper aftercare and lifestyle adjustments can help sustain the effects of skin whitening treatments and prevent pigmentation from returning

IC50 was calculated according to cell viability using the nonlinear regression analyses in GraphPad Prism 10.0 software

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We performed model cross-validation using leave-one-out in rstan

However, markedly elevated levels without supplementation may warrant GP review to exclude underlying conditions such as haematological disorders, liver disease, or renal impairment