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CTL: cytotoxic T lymphocyte

The California Geographer/The California Geographical Society

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If in fact future studies robustly establish a beneficial effect of the drug class in HF, it may allow for broader adoption of GLP-1 RAs in the prevalent CVD, ultimately contributing to addressing the unmet medical need that continues to persist in the prevention or management of, in particular, HFpEF

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Particularly, genes involved in lipid metabolism ( Abcg5 ), drug metabolism ( Cyp2a4 ), GSH metabolism ( Gstm2 and Gstm6 ), and oxidative phosphorylation ( Lhpp ) were expressed at higher levels in the liver of hepsin / mice compared with wild-type mice