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Glucagon also inactivates acetyl-CoA carboxylase (ACC), which creates malonyl-CoA from acetyl-CoA, through cAMP-dependent and/or cAMP-independent kinases

doi:10.1093/mmy/myu026

For the screen, 300 10 6 MCF-7 iCas9 cells were infected at a multiplicity of infection (MOI) of 0.3, aiming for 1000 cells per individual sgRNA, with a previously published and validated genome-wide human lentiviral CRISPR library 17

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The length of hospital stays and recovery rates of the three groups were compared