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The September approval was based on data from a Phase 3 clinical trial called JETALS (NCT03548311), in which Rozebalamin significantly slowed ALS disease progression when given alone or in combination with standard ALS treatments

From that biology, researchers draw a theoretical concern: chronically potentiating a proliferative, pro-angiogenic pathway is a plausible mechanism by which an agent could, in principle, support growth of existing malignancy

Beyond direct immune signaling, BAs significantly influence systemic inflammation by modulating intestinal permeability

It leads to nerve damage and neurological issues

You can also find vitamin B12 in cheese and yogurt