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Patients on any oral antihyperglycemic agent in monotherapy (N=212) or on a PPAR agent in combination therapy (N=106) or not on an antihyperglycemic agent (off therapy for at least 8 weeks, N=34) were switched to monotherapy with pioglitazone (at a dose of 30 to 45 mg per day) and completed a run-in period of approximately 12 weeks in duration

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GLP-1 and GIP receptor signaling in beta cells a review of receptor interactions and co-stimulation

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J.MathieuC.DuretL.GallesiD.Van de SypeG.HrouartD.PuppoA

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