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Fluorescence measurements were performed using a BioTek Synergy 2 microplate reader with excitation wavelength of 581 nm and an emission wavelength of 591 nm

While purine nucleotide synthesis is selectively affected through Nrf2 activation, c-Myc is involved in the regulation of both purine and pyrimidine nucleotide synthesis

The amino acid sequence of the product is identical to that of endogenous human IGF-1

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Reduced lysosomal acid lipase activitya potential role in the pathogenesis of non alcoholic fatty liver disease in pediatric patients