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2) Abnormally elevated CD163+ macrophages drive excessive complex phagocytosis, leading to macrophage iron overload, LIP expansion, oxidative stress, and ferroptosis

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Conclusion: Understanding biweekly dosing Although biweekly dosing is not approved by the FDA, it is becoming a common off-label practice

Side effect comparison All three compounds share a similar gastrointestinal side effect profile, which is expected given that all three activate the GLP-1 receptor

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