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(D) Bar graphs and dots summarize the number of -end (+) cells from DT-injected iDTR mice (black, n =4) and DT-injected iDTR:: Pomc -Cre mice (red, n =3)

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In addition to a regulatory role in intrarenal RAS homeostasis, megalin seems also to indirectly contribute to atherosclerosis development increasing renal ANG II levels (40)

Die Rezeptoraktivierung erhht das intrazellulre cAMP und reguliert MITF sowie Tyrosinase hoch, was die Eumelaninsynthese antreibt den Signalweg, der der Pigmentierungs- und Photoprotection-Forschung zugrunde liegt

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