Without sufficient protein intake and the right exercise or muscle-stimulating protocols, up to 40% of weight lost on GLP-1 drugs like Ozempic and Wegovy can come from lean muscle mass, impacting strength and metabolism
GLP-1 is able to stimulate cAMP formation in RIN 1046-38 cells, which in turn causes an increase in insulin mRNA levels and insulin release, and insulin accumulation in the culture fluid was observed by adding GLP-1 (7-37) to RIN 1046-38 cells for 1 h incubation (Mojsov et al., 1987)
Extremophiles, 21 (5), 933945
Carillon J, Fouret G, Feillet-Coudray C, Lacan D, Cristol JP, Rouanet JM
Understanding how the supplement claims to work at each location helps evaluate whether the approach is scientifically grounded or primarily a marketing framework
When you eat less, you also consume fewer electrolytes from food