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Based on the studies reviewed, the role of GLP-1 RAs may be for patients who have optimized a basal insulin regimen and are 0.5% to 1.5% away from achieving their A1C goal
This is due to the nature of the included studies, which were primarily registry-based and ongoing, with limited or unavailable outcome data
And I was like, this is so interesting
Higher doses (90 mg and 120 mg) achieved up to 12.2% mean reduction from baseline (26.6 lbs) versus 1.3% (2.9 lbs) for placebo, with up to 97% of patients losing 5% of body weight
Mitochondrial dysfunction, apoptosis and oxidative stress are in part due to methylglyoxal accumulation
FAQs: Supplements for Ozempic, Wegovy and other GLP-1 medications Is berberine safe to take with a GLP-1
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