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Mayo, J

Dose escalation, medication switching, or combination therapy (like GLP-Squared) frequently reignite weight loss and appetite suppression

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The use of peptide dual agonists of the glucagon receptor (GCGR) and the glucagon-like peptide-1 receptor (GLP-1R) is one of the treatment options being researched and evaluated clinically for diabetes, obesity, and related conditions

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Modulating these pathways is therefore an area requiring careful characterisation in research