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In order to maintain low levels of reactive oxygen species (ROS), ascorbate peroxidase (APX) and GPX convert hydrogen peroxide to water in the ascorbate (AsA)-glutathione (GSH) cycle and oxidized glutathione (GSSG)-GSH cycle, respectively [8, 9]

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Using the CMap dataset, we identified a relationship between the gene expression changes induced by the tripeptide GHK and those that are repressed with increasing emphysema severity