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Furthermore, genome-wide CRISPR screening identified SEC24 homolog B (SEC24B) as a key regulator of ferroptosis, and its knockout significantly inhibited ferroptosis in microglia (Ryan et al., 2023b)

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Any study that appeared to meet the predefined eligibility criteriaoutlined in Table 1 and focused on the role of GLP-1 agonists in body weight regulation and neuroprotection, was selected for further evaluation and full-text review

Inflammasomes: mechanism of action, role in disease, and therapeutics