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The most frequently reported local issues included redness, slight swelling, or itching at the point of injection

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Swab the planned injection site gently with the alcoholic swab and allow to dry Step 16

There may also be temporary erythema and burning shortly after application

In clinical practice, providers often observe that patients who progress steadily through lower stages without significant gastrointestinal symptoms tend to tolerate increases toward the higher tiers more comfortably than those who experienced ongoing discomfort earlier in treatment