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**Patients without diabetes and with BMI 30, or BMI 27 plus a weight-related condition, lost an average of 20% of their body weight by 1 year in a 72-week trial studying the highest maintenance dose of Zepbound (15 mg), when paired with diet and exercise changes (compared to 3% with diet and exercise alone)

The question of whether semaglutide directly causes pancreatitis remains an area of ongoing investigation, with current evidence suggesting a possible association rather than a confirmed causal relationship

They work by mimicking the action of a naturally occurring hormone called glucagon-like peptide 1

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After propensity score matching, the analytic cohort comprised 26,408 matched patients: 13,204 users and 13,204 non-users

Cao, C., Yang, S