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To avoid problems due to species specific differences in drug transporters at the BBB [36] human cell-based models are preferable

[DOI] [PMC free article] [PubMed] [Google Scholar] 2.Molehin O.R., Adefegha S.A., Adeyanju A.A

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This mechanism explains how urate crystal deposition in joints induces gout [13] and cholesterol crystals in vascular walls promote atherosclerosis [14]

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