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Quite remarkably, in those with low POP levels, the typically robust association between diabetes and obesity was not observed in a nested case-controlled study, suggesting that obesity may exaggerate the metabolic disturbances caused by POPs (perhaps because adipose tissue provides a reservoir for fat-soluble toxins), rather than being directly responsible for the altered metabolism

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This drug has shown significant protective effects in various preclinical models, including retinal cells (232)

PMID: 37844869

Immune cells are likely affected by G6PD-d in two major ways

The plasma supernatant was aliquoted, snap-frozen in liquid nitrogen and stored at 80 C before analysis