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Here we show that oral intake of long-term oscillating glucose (LOsG) (4 times/day) for 38 days, which produces physiological glycemic variability in rats, can lead to -cells gaining metabolic memory in reactive oxygen species (ROS) stress

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Richard Pazdur, a 26-year veteran at the FDA, said he was retiring, just weeks after accepting the role as CDERs director

Individuals with seizure disorders or psychiatric conditions should exercise caution, as high ammonia levels may exacerbate these conditions

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Patients should monitor for signs of dehydration , particularly if experiencing significant gastrointestinal symptoms