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At week 16, DAPA + SITA + MET ER showed significant reduction in postprandial blood glucose compared to DAPA + MET ER ( p = 0.0394) and significant reduction in fasting blood glucose with DAPA + SITA + MET ER compared to SITA + MET SR ( p = 0.0226)

Weight loss itself can also shift how your body distributes fluids and regulates blood pressure, compounding the effect

For best results, individuals should work closely with healthcare providers to adjust medication timing and address persistent sleep challenges through personalized interventions