One 2026 narrative review concluded that GLP-1 receptor agonist therapy is associated with meaningful nutritional deficiencies and that individualized nutritional assessment and lab evaluation may be appropriate, especially in people at higher risk of malnutrition
The drugs very mechanismslowing gastric emptying and affecting blood sugar controlmakes gastroparesis and related complications predictable consequences, not rare adverse effects
The combination also increases the risk of nausea and can further stress the GI tract during the window when side effects are already most likely
And brands, including Wegovy and Ozempic, often cost around $1,000 per month out of pocket
M., Houshmand-Oeregaard, A., Laursen, P
A stoppage period shorter than four half-lives has questionable benefits