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But beneath the hype and fear is a simple story: these drugs target a core metabolic signaling pathway that influences cardiovascular health, inflammation, cognition, kidney function, and long-term resilience

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Other AEs include increase in heart rate and injection-site reactions (excluding oral semaglutide) [16, 18, 20, 22, 24, 26]

Second, research in animal models suggests that semaglutide activates GLP-1 receptors in the central nervous system, particularly in the brainstem area postrema and nucleus tractus solitarius, which are regions responsible for controlling nausea and vomiting responses