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Gastrointestinal Effects The most frequent adverse effects of GLP-1RAs are gastrointestinal, including nausea, vomiting, diarrhoea and a sensation of early satiety

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However, human studies showed that improvements in pain are predominantly attributed to weight loss, rather than direct analgesic effects in the condition of osteoarthritis [47]

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Ro recently published the first study to evaluate both the long-term weight loss and safety outcomes of treatment with semaglutide via telehealth