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Laboratory Abnormalities Liver Enzymes Increases in alanine aminotransferase (ALT) greater than or equal to 10 times the upper limit of normal were observed in 5 (0.15%) SAXENDA-treated patients (two of whom had ALT greater than 20 and 40 times the upper limit of normal) compared with 1 (0.05%) placebo-treated patient during the SAXENDA clinical trials

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Recent research has shown that GIP helps reduce oxidative stress in human endothelial cells and prevents the release of inflammatory cytokines in visceral adipose tissue [59]

Learn More A once-weekly, lower-dose agonist (GLP-1) designed for a gentler start and to minimize side effects

Future investigations are required to establish therapeutic target for purinergic drugs in treatment of SZ patients

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