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From the point of view of clinical relevance, pathophysiological responses to GLP-1 demonstrated in current study including acute increases in RSNA, MAP and HR and decreases in diuresis and natriuresis, all features that are likely to be unfavorable and might contribute to a greater risk for HF

Here's what Truist Securities analyst Jailendra Singh had to say about the latest developments after speaking to investors: - "Some investors have also argued that, it could take 2-3 years before supply constraints are resolved and, by that time, GLP-1 offerings like HIMS would have already gotten a lot of traction and would be hard to back down from, given the price point." - "Some investors are worried that this could be very short-term and last only until the branded drugs supply shortage is resolved." - "Some investors also raised concerns around potential pushback from pharma manufacturers with a reference made to recent Lilly's settlement agreement with Totality Medispa on compounding products." Investors and Consumers should be aware that the FDA does NOT typically review or approve the Quality and Safety of compounded GLP-1 medications

GLP-1 receptor agonists are effective in reducing glucose, enhancing satiety, promoting weight loss, and lowering cardiovascular risks in high-risk patients