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Due to the toxic effects of homocysteine on blood vessels, high homocysteine is linked to increased risk of cardiovascular and microvascular diabetes complications

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Theres also dysesthesia, a burning, prickling skin sensation that hit roughly one in eight high-dose patients in the obesity trial and up to one in five in the knee trial, something earlier GLP-1s mostly dont cause

By 12 months off medication, most research participants have regained 60 to 70 percent of the weight they lost

Consistency: The single biggest variable

The online forums contradict each other