Although the proton leak was not measured in this study, the accumulation of malonyl-CoA should increase fatty acid synthesis and thus activate UCPs
Most patients experience gradual symptom improvement over weeks to months after discontinuation
You should not take Imigran if you: Are allergic to sumatriptan Have heart disease such as angina or a history of heart attack Have circulation problems in your legs (peripheral vascular disease) Have had a stroke or transient ischaemic attack (TIA) Have uncontrolled high blood pressure Have severe liver disease Are taking medicines containing ergotamine or similar medicines such as methysergide Are taking other triptans (5-HT1 receptor agonists) Are taking MAOIs or have taken them in the last 2 weeks If you are pregnant, speak to a healthcare professional before using Imigran
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Canadian journal of physiology and pharmacology
