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It is essential to administer intranasal and intravenous routes to the same animal species to calculate B(X) using Equation 3, where B(IV) is the brain AUC following intravenous administration, while P(IV) and P(IN) correspond to the plasma AUC after intravenous and intranasal administration, respectively

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Vision Changes : Report any vision changes, particularly if you have pre-existing diabetic retinopathy

The best place to inject tirzepatide is one of the three recommended injection sites: Abdomen Front, outer thigh Upper arm (if someone is helping you) If youre self-injecting, its best to choose your stomach (at least 2 inches away from your belly button) or the front part of your outer thigh

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doi: 10.1161/01.cir.94.10.2417