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Comprehensive profiling across distinct immunological niches in 5xFAD mice, reveals a high level of disease-associated CD4 + T cells that produce IL-17A in the dural meninges, previously linked to cognitive decline
In fact, a cell is now considered to be healthy if it has a GSH/GSSG ratio of more than 100, ie a much higher amount of GSH than GSSG
J Psychopharmacol 31(9):11491165 Achtyes E et al (2020) Inflammation and kynurenine pathway dysregulation in post-partum women with severe and suicidal depression
doi: 10.1111/j.1432-1033.1986.tb09668.x
Following reports of bacterial endotoxin in the pelvic cavity and menstrual blood 37 , and sub-clinical uterine infections found in patients with endometriosis 56 , Khan et al., 2017 proposed that microbes might activate inflammatory cascades by binding Toll-like receptors, and contribute to endometriotic lesion establishment, growth and progression