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Historically, immunohistochemical confirmation has been hampered by the poor specificity of anti-GLP-1R antibodies (11), but better performing antibodies have enabled the distribution of GLP-1R to be more confidently ascertained in rodents, monkeys and humans (1214)

Nutrition and living a healthy lifestyle have always been a cornerstone in Courtneys life

It can either enhance or reduce the effect of these drugs, leading to unstable blood sugar levels

However, practical guidance for clinicians to implement such an approach is limited

65,66,67 Although the risk factors for PDPN are poorly understood, female sex, longer diabetes duration, increased neuropathy severity, renal dysfunction, higher HbA1c levels, and higher BMI have been suggested as contributing factors

Even more frustrating