Targeting mitochondrial dysfunction in the treatment of heart failure
Dietary polyunsaturated fatty acids and heme iron induce oxidative stress biomarkers and a cancer promoting environment in the colon of rats
This, in turn, leads to reduced brain tryptophan concentration, decreased 5-HT levels, and diminished 5-HT receptor binding, which may underlie the 5-HT system dysfunction, impaired neurotransmission, and negative cognitive effects observed in SZ
"Somatostatin and thyrotropin releasing hormone: central effect on sleep and motor system." Pharmacology Biochemistry and Behavior
SC: 5-10mg per injection, 2-3 times per week
The existing amylin analogue pramlintide (sold as Symlin in the US for diabetes management) requires multiple daily injections