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Discussion The efficacy and safety of therapeutic agents are significantly influenced by individual patient variations, disease complexity, and drug metabolism

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Tips to Prevent Melanin from Sun Exposure: Use Sunscreen: Apply a broad-spectrum sunscreen with SPF 30+ or above on your skin to avoid UV-induced pigmentation

Agarwal A, Chang GJ, Hu CY, Taggart M, Rashid A, Park IJ, You YN, Das P, Krishnan S, Crane CH, Rodriguez-Bigas M, Skibber J, Ellis L, Eng C, Kopetz S , Maru DM