Cytokine profiling using immunology multiplex assay MCP-1/CCL2, IL-6, and TNF-alpha (TNF) were measured in fasted plasma collected at endpoint using the Milliplex MAP Mouse Metabolic Hormone Magnetic Bead Panel in the Luminex MAGPIX system (EMD Millipore, Billerica, MA)
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The FDA approved Wegovy for weight loss in 2021
Propensity matching was used to assess whether prescribed semaglutide was associated with NAION in patients with type 2 diabetes (T2D) or overweight/obesity, in each case accounting for covarying factors (sex, age, systemic hypertension, T2D, obstructive sleep apnoea, obesity, hyperlipidemia, and coronary artery disease) and contraindications for use of semaglutide
Support from dietitians or structured programmes can help