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Otro aspecto relevante es que, en ciertas condiciones mdicas como insuficiencia renal, trastornos metablicos hereditarios o enfermedades cardiovasculares, los niveles de L-Carnitina pueden verse comprometidos, lo que refuerza la necesidad de un aporte externo

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Mechanisms identified include: increased cardiac utilization of ketones increased autophagy (recycling of intracellular components)l decreased inflammation & oxidative stress improved mitochondrial function decreased intracellular Ca & Na overload decreased fibrosis improved myocardial diastolic function decrease myocardial hypertrophy Figure 1