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Description

Figure 3 4 Targeting lipid metabolism for DKD treatment 4.1 Conventional drugs 4.1.1 Atorvastatin Atorvastatin effectively reduced the levels of low-density lipoprotein CHOL (LDL-C), creatinine (CREA), and urinary albumin and creatinine (UACR) and downregulated the expression of the inflammatory factors TNF-, monocyte chemoattractant protein-1 (MCP-1), and IL-6 expression in renal tissues, which ameliorates renal injury and delays the progression of DKD by reducing morphological lesions and renal fibrosis and increases transforming growth factor beta (TGF-) and collagen I staining (185)

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