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Concentration-wise, this ingredient is rarely used pure and usually shows up as part of a standardized centella extract where reported content ranges from 0.02-3.06%

The tests are simple to administer and take and are widely available

The clinical implications, however, depend on whether the mechanism translates to humans and whether the doses used produce meaningful c-Met activation in human brain tissue

targeted supplementation is most valuable when it addresses a specific nutritional shortfall confirmed by food tracking or lab results rather than used as a substitute for consistent lifestyle habits

Abbreviations: CoQ, Coenzyme Q

In diabetic rat models, MOTS-C treatment improved myocardial mechanical efficiency and enhanced both systolic and diastolic function